Ryuhjin Ahn, Alicia D. D’Souza, Lawrence Long, Yufei Cui, Danielle Burgenske, Katrina K. Bakken, Lauren L.Ott, Brett L. Carlson, Grace Zhou, Tomer M. Yaron-Barir, Ishwar N. Kohale, Charles A. Whittaker, Cameron T. Flower, Jeffrey Wyckoff, Ann Tuma, Jared L. Johnson, Jann Sarkaria, Forest M. White Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT.bioRxiv 2024.12.04.626717

Tigist Y Tamir, Shreya Chaudhary, Annie X Li, Sonia E Trojan, Cameron T Flower, Paula Vo, Yufei Cui, Jeffrey C Davis, Rachit S Mukkamala, Francesca N Venditti, Alissandra L Hillis, Alex Toker, Matthew G Vander Heiden, Jessica B Spinelli, Norman J Kennedy, Roger J Davis, Forest M White Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity bioRxiv 2024.08.28.609894

Yufei Cui, Kien Phuong, Heidi Temple, Amy J. Wisdom, Nouran S. Abdelfattah, StefaniSpranger, Forest White Analysis of tumor-derived and cross-presented peptide antigens defines improved immunotherapeutic strategies bioRxiv 2026.02.23.707477

Ying Jiang, Ryuhjin Ahn, Arthur Huang, Phillippe P. Gonzalez, Jungeun Kim, GuoxinZhang, Zihao Liu, Zhenqiang He, Lindsey Dudley, Kunal S. Patel, Godfrey A. Dzhivhuho, Sam Crowl, Piotr Przanowski, Luisa Quesada Camacho, Sijie Hao, Jianhao Zeng, SimonHippenmeyer, Mohammad Fallahi-Sichani, Kevin A. Janes, Kristen M. Naegle, Marie-Louise Hammarskjold, Steven A. Goldman, Harley I. Kornblum, Maojin Yao, ForestWhite, Hui Zong Critical role of cell competition in gliomagenesis bioRxiv 2026.01.15.699808

Flower CT, White FM. Tyrosine phosphoproteome profiling identifies cell-intrinsic signals limiting the efficacy of tyrosine kinase inhibitor therapies. Proc Natl Acad Sci U S A. 2026 Mar 31;123(13):e2522090123. doi: 10.1073/pnas.2522090123. Epub 2026 Mar 25. PMID: 41880579; PMCID: PMC13037951.

Leddy O, McGinn R, Allsup B, Leone M, Timms P, Gutierrez-Gonzalez M, Fahad AS, Milligan R, Garcia-Beltran WF, DeKosky BJ, White FM, Bryson BD. Control of antigen presentation on MHC-I by a bacterial secretion system. bioRxiv [Preprint]. 2025 Nov 20:2025.11.19.689332. doi: 10.1101/2025.11.19.689332. PMID: 41332634; PMCID: PMC12667757.

Rizzo S, Hart WS, Fetter RL, Song B, White FM, Lazzara MJ, Thévenin D. PTPRJ-Targeting Peptide Agonist Induces Broad Cellular Signaling Perturbations and DNA Damage in Lung Cancer Cells. bioRxiv [Preprint]. 2025 Nov 17:2025.11.17.688709. doi: 10.1101/2025.11.17.688709. PMID: 41332557; PMCID: PMC12667812.

Choe EY, Leddy O, Riviere-Cazaux C, Burgenske DM, Hu Z, Mladek AC, Fedeles BI, Hu S, Essigmann JM, Prins RM, Sarkaria JN, Burns TC, Vaubel RA, White FM. Systems analysis uncovers early temozolomide responses and peptide antigens in glioblastoma. bioRxiv [Preprint]. 2025 Nov 12:2025.11.10.687735. doi: 10.1101/2025.11.10.687735. PMID: 41292792; PMCID: PMC12642668.

Pribyl LJ, Kay JE, Corrigan JJ, Volk LB, Norales M, Owiti NA, Kowal EA, Kohale IN, Nazari IS, Swanson MR, Moise AC, Ma D, Levine SS, Michelsen E, Croy RG, Ragan T, Torous DK, Avlasevich SL, Dertinger SD, Carrasco SE, Samson LD, Essigmann JM, White FM, Engelward BP. Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer. bioRxiv [Preprint]. 2025 Oct 3:2025.10.01.679856. doi: 10.1101/2025.10.01.679856. PMID: 41256671; PMCID: PMC12621704.

Leddy O, Ogongo P, Huffaker J, Gan M, Milligan R, Mahmud S, Ni HM, Yuki Y, Bobosha K, Wassie L, Carrington M, Liu Q, Ernst JD, White FM, Bryson BD. Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens. Sci Transl Med. 2025 Nov 5;17(823):eadw9184. doi: 10.1126/scitranslmed.adw9184. Epub 2025 Nov 5. PMID: 41191777.

Ling AL, Gantchev J, Prabhu MC, Basu S, Ahn R, D'Souza A, Masud N, Ball A, Nikas O, Villa GR, Regan MS, Baquer G, Ayoub G, Whittaker CA, Abou-Mrad Z, Santos A, Couturier CP, Elharouni D, Vogelzang J, Yu KKH, Chen H, He Z, Jiang W, Lucas CH, Sax HE, Lang FF, Puduvalli VK, Tabar V, W Brennan C, Boire A, Holdhoff M, Bettegowda C, Cima M, Solomon IH, Yuan Y, Tak PP; Accelerating GBM Therapies TeamLab; Sharma P, White FM, Ligon KL, Agar NYR, Reardon DA, Oliveira G, Chiocca EA. Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses. Sci Transl Med. 2025 Oct 8;17(819):eadv2881. doi: 10.1126/scitranslmed.adv2881. Epub 2025 Oct 8. PMID: 41061048.

Cui Y, Phuong K, Abdelfattah NS, Temple HM, Maiorino L, Kim BJ, Dye J, Yu KKH, Spranger S, Irvine DJ, White FM. Quantitative Cell Type-Specific Immunopeptidome Analysis of Macrophage and Tumor Coevolution Reveals Therapeutic MHC-I Peptides in Glioblastoma. Cancer Res. 2025 Dec 15;85(24):4958-4976. doi: 10.1158/0008-5472.CAN-24-4674. PMID: 40966317; PMCID: PMC12616400.

Leddy O, Yuki Y, Carrington M, Bryson BD, White FM. Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery. J Exp Med. 2025 Oct 6;222(10):e20250444. doi: 10.1084/jem.20250444. Epub 2025 Jul 21. PMID: 40689854; PMCID: PMC12279011.

Tamir TY, Chaudhary S, Li AX, Trojan SE, Flower CT, Vo P, Cui Y, Davis JC, Mukkamala R, Venditti FN, Hillis AL, Toker A, Vander Heiden MG, Spinelli JB, Kennedy NJ, Davis RJ, White FM. Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity. Mol Cell. 2025 Jun 5;85(11):2211-2229.e8. doi: 10.1016/j.molcel.2025.05.007. Epub 2025 May 28. PMID: 40441152; PMCID: PMC12147527.

Migliozzi S, Adabbo B, Garofano L, Wu F, Davila P, Komotar RJ, Ivan ME, Shah AH, Currall BB, Williams S, Bilbao Cortes D, Minucci Boone M, de la Fuente MI, Gultekin SH, Ceccarelli M, Iavarone A, Lasorella A. Restraint of cancer cell plasticity by spatial homotypic clustering. Cancer Cell, 43:2206-2223, 2025 [see also PREVIEW “Spatial patterns of glioblastoma” Cancer Cell, 43:2189-2190, 2025].